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Generate beta matrix giving genetic effect per SNP on taxa abundances.

compute_beta_matrix_cluster.Rd

Generate beta matrix giving genetic effect per SNP on taxa abundances.

Usage

compute_beta_matrix_cluster(
  n_b,
  n_g,
  n_clust,
  n_qtl_o,
  n_otus,
  effect_size = 1,
  correlation = 1,
  beta_info = NULL
)

Arguments

n_b

Number of taxa

n_g

Number of SNPs

n_clust

A vector with a length matching the total number of taxa with values from 0 to the number of clusters. Typically the assign_taxa() output.

n_qtl_o

Number of causative QTL on taxa abundances (per taxon)

n_otus

Number of taxa under genetic control.

effect_size

Vector giving the size of genetic effect to try

correlation

A numeric value between 0 and 1 representing the target correlation between taxa within the same cluster.

beta_info

Informations from Beta matrix of genetic effects

Value

A list of two objects linked to the beta matrix. The beta matrix itself : a matrix of taxa (in rows) across SNPs (in columns) giving the multiplicative effect of genotype on taxa abundances. A small data.frame containing the parameters used during the beta matrix simulation, including cluster, id_otu and id_qtl_o.

See also

compute_beta_g(), holo_simu()